INTRODUCTION

Our PrestigiousHospital which was situated in salem town was started in 1917 in order to serve the people of salem and

- The foundation of our GMKMcollege in Steel plant road was laided by our honourable prime Minister Late.shri.Rajiv Gandhi on 25 th October 1988.

- The first batch was started with admission of 75 M.B.B.S students from July 1990.

-The base of Biochemistry department was renovated in 1991 .

-The department of Biochemistry, GMKMC, under the leadership of able professors and dedicated faculties, has played a monumental role in strengthening the foundations of countless medical students, for Biochemistry is one of the three basic subjects to be mastered in the first year of their under graduate study.

- The Clinical Biochemistry laboratory provides round the clock services in aiding the diagnosis and management of the ever increasing number of patients who attend the GMKMC Hospital from in and around Salem.

-The department also gives extensive training and imparts high degree of professional competency to Post graduates ,M.B.B.S students, Medical Laboratory Technology students(2Yrs),BscMLT(3yrs),CT,OT,AT students in addition to educating Nursing and other paramedical students on the essentials of biochemistry.

ADMINISTRATION

TEACHING PROGRAM

- The annual intake of MBBS students increased to from 75 to 100, so did the intensity of academic activities focused on student excellence. Apart from regular class schedules, tutorial classes and Internal assessment exams in theory/ practical’s, the students are subjected to weekly tutorial tests and regular assignments, prodding them to pursue their lessons with deeper understanding and thoroughness, and to enhance their performance in the University examinations.

- As another means of intellectual stimulation, the students are required to present seminars/ symposia on various topics, using power point presentations, charts and other audio visual aids, during their period of study in the department.

- The department also makes sure that the parents are informed regarding their children’s progress by sending the attendance and mark particulars of students every three months. The parents in turn respond by coming to the department periodically to meet the HOD and staff to discuss the performance of their children, which helps in encouraging them to perform better.

- In addition, the department organizes and participates in horizontal and vertical Integrated teaching programs to provide the students a bird’s eye view of the concerned topic.

Integrated Teaching Programs of every academic year, involves the departments of Anatomy, Physiology and Biochemistry, also with microbiology, Generalmedicine and general surgery about the following topics

CME/CLE PROGRAMMES CONTINUING LABORATORY EDUCATION CONDUCTED

TOPIC : SETTING UP OF A BIOCHEMISTRY LAB WITH BASIC INSTRUMENTS – WORKSHOP

DATE : 01.03.2023

VENUE : COLLEGE AUDITORIUM

This hands on training was arranged for paramedical students like DMLT , Bsc MLT Around 300 students participated from in and around Salem Training was given to set up a basic clinical laboratory .

Calibration and quality control in semi auto analyser was discussed and explained.

Trouble shooting ,dismantling ,simple repair were taught for semi auto analyser.

Programming of analytes in semi auto analyser was explained.

Work shop on trouble shooting and repair, hands on training in micropipette, colorimeter, centrifuge was given .

Students presented posters.

Click on the Image

UPCOMING EVENT:

QUIZ :ZONAL LEVEL QUIZ FOR FIRST YEAR MBBS STUDENTS

DATE :13.09.2023

VENUE : COLLEGE AUDITORIUM

ACADEMIC ACTIVITIES

-COURSES INCLUDED IN THE TEACHING CURRICULUM

-Medical

• MBBS 1st year
• M.D Biochemistry

-Paramedical

• DMLT 1st& 2nd years
• BscMLT 1,2,and 3rd years
• BSc Nursing – Basic and Post basic
• One month Orientation lectures are given to the following paramedical courses to teach them the basics of Biochemistry:

Anesthesia technician

CMLT

Dialysis technician

DRDT

DRTT

ECG technician

Theatre technician

Emergency care technician

Nursing assistant

Ortho technicia

Radiology technician

STANDRAD SCHEDULE

1.M.B.B.S. STANDRAD TEACHING SCHEDULE

• Integrated session once in 2 months.
• Early clinical exposure once in 3 months.
• Quiz once in a year.
• Theory internal assessments every 6 weeks.
• Practical internal assessment once in 2 months.

2.BSc. MLT STANDARD TEACHING SCHEDULE

• Four theory classes and one practical class in a week.
• Intensive lab training weekly once in hospital lab.
• Theory internal assessments every 3 months.
• Practical internal assessment once in 3 months.
• Exclusive internship for 4 months after completion of the course.

3.NURSING STANDARD TEACHING SCHEDULE

• Two theory classes in a week covering basic biochemistry topics.
• Theory internal assessments every 3 months.

4.Bsc. CARDIAC TECHNOLOGY / OT TECHNOLOGY STANDARD TEACHING SCHEDULE

• Two classes in a week covering basic biochemistry topics.
• Internal assessments every 3 months.

5.DMLT STANDARD TEACHING SCHEDULE

• Five theory classes and two practical classes in a week.
• Intensive lab training on alternate months in Biochemistry, Pathology and Microbiology in rotation.
• Theory internal assessments every 3 months.
• Practical internal assessment once in 3 months.
• Exclusive internship for 3 months after completion of the course.

NOTEWORTHY PERFORMANCE IN MBBS UNIVERSITY EXMINATIONS

2008-2009 - 100% PASS

1999-2000 - UNIVERSITY FIRST- Dr. SUBITHA

2005-2006 - UNIVERSITY FIRST- Dr. KARTHICK

2013-2014 - No. of DISTINCTIONS- 15; HONOURS- 3

2016-2017 - No. of DISTINCTIONS- 19; HONOURS- 11

2017-2018 - No. of DISTINCTIONS- 17; HONOURS- 2

2019-2020 - No. of DISTINCTIONS- 14; HONOURS- 1

2020-2021 - No. of DISTINCTIONS- 13 ; HONOURS- 3

P.G COURSE

Three post graduate seats has been sanctioned for the academic year 2016-2017

Three post graduates joined in M.D(BIO) from the academic year 2016 -2017 .Continued till date 3 post graduates per year

LABORATORY SERVICES

-The clinical Biochemistry laboratory functions within the premises of the GMKMC Hospital, manned by qualified medical officers and efficient technical staff members.

-Blood samples are collected through the common collection center. The amply equipped central lab and the 24 hour emergency lab, operate to analyze the in-patient, out-patient, NCD (Non Communicable Diseases) OP, Master health check up and emergency cases effectively and have been instrumental in helping the clinicians treat the thousands of ailing patients the vast hospital caters to.

- The lab investigations are performed in the

1. fully automated Biochemistry analyzers and
2. semi automated Biochemistry analyzers. The fully automated analyzer XL-640 has been imperative for the functioning of the lab due to its accuracy, precision, speed and economical usage of the reagents.
3. Electrolyte analyser
4. ABG Analyser
5. HbA1C Analyser
6. CLIA-Hormones
7. Electrophoresis
8. HPLChromatography-Mainly for screening Hemoglobinopathies

Haemoglobinopathy screening programme was started in our lab since 2018 and was doing nrearly 200 samples every month.We are receiving samples from all nearby hilly regions like Kollihills,yercaud and Kariyalur (kallakuruchi) .

QUALITY CONTROL

The clinical Biochemistry lab of GMKMCH is under the ACBI/CMC External Quality Assurance (EQAS) program of Christian Medical College, Vellore, keeping a check on the quality of the tests done. The results are sent every month and reports are obtained ensuring satisfactory performance of the lab.

LIST OF INVESTIGATIONS DONE

BLOOD:

1. SUGAR
2. UREA
3. CREATININE
4. LIPID PROFILE -TOTAL CHOLESTEROL
5. -DO- - HDL CHOLESTEROL
6. -DO- -TRIGLYCERIDES
7. BILIRUBIN – TOTAL & FRACTIONS
8. TOTAL PROTEINS
9. ALBUMIN, AG RATIO
10. URIC ACID
11. CALCIUM
12. PHOSPHORUS

ELECTROLYTES –

1. SODIUM,
2. POTASSIUM,
3. BICARBONATE,
4. CHLORIDE

ENZYMES

1. SGOT (AST)
2. SGPT (ALT)
3. LACTATE DEHYDROGENASE (LDH)
4. CREATINE PHOSPHOKINASE (CPK)& (CPK MB)
5. AMYLASE
6. ACID PHOSPHATASE (ACP)
7. ALKALINE PHOSPHATASE (ALP)
8. GAMMA GLUTAMYL TRANSPEPTIDASE (GGT)
9. CHOLINESTERASE
10. GLUCOSE TOLERANCE TEST

Special investigations

1. ABG
2. THYROID FUNCTION TESTS
3. VIT.B12
4. VIT D
5. S.FERRITIN
6. HBA1C
7. CRP
8. METABOLIC SCREENING TESTS
9. ELECTROPHORESIS
10. HPLCHROMATOGRAPHY-HEMOGLOBINOPATHY SCREENING
11. S.INSULIN
12. CEA
13. CA19/9
14. AFP

URINE ANALYSIS

1. 24 HOURS URINE PROTEINS
2. URINE PCR

FLUID ANALYSIS

1. CEREBROSPINAL FLUID
2. ASCITIC FLUID
3. PLEURAL FLUID

STONE ANALYSIS

Biochemical analysis of Renal/ Salivary/ Gall stones

-In addition during the covid period our laboratory did all the covid inflammatory markers as 24hr services and served the people well.

STATISTICS OF THE INVESTIGATIONS DONE

MONTHLY STATISTICS FOR THE YEAR 2023

ON GOING PROJECT

A comparative study of serum pentraxin -3 levels and high sensitivity CRP levels in Patients with diabetic nephropathy – Dr Nithya

Study of sestrin -2 as a predictive biomarker for atherosclerosis in type 2 diabetes in a tertiary care hospital – Dr Mithun

Study of serum Lp -PLA 2 ( Lipoprotein associated phospholipase A2 in metabolic syndrome patients – Dr Nandhini

RESEARCH ACTIVITIES

The Department advocates staff- student interaction that nurtures research mindedness among the budding doctors.

-Over the years quality research projects have been undertaken by the students, many funded by the ICMR. The notable ones are listed below:

1. Biochemical Profile in Nephrotic syndrome
2. Glycosylated Hemoglobin in newly detected diabetic patients in various age groups- a prospective study
3. Spot urine Creatinine:Protein ratio – can it replace 24 hours urine protein estimation
4. Screening of Hemoglobin variations- a hospital based prospective study
5. Serum & 24 hour urinary Calcium and Uric acid in Renal stone formers
6. Microalbuminuria in Non-Insulin Dependent Diabetes Mellitus
7. Assessment of Calcium balance in nephrotic children
8. Serum Lactic acid, lactate clearance and Uric acid levels in Acute Coronary Syndrome
9. A Case Control Study of Predictors of Myocardial Infarction in the Post covid and Noncovid patients among the risk Population of Salem District- Dr.Kalaiselvi M.D(BIO),Dr.Gayathri sethurajan CRRI
10. STS2020,REF.ID:202006946,Title:Comparision ofthyroid function between individuals with chronic kidney disease and healthy population –A faculty based crosssectional study in tertiary care hospital-Dr.Sageetha ,M.D(BIO),Dr.Raveena (student)

COMPLETED PROJECT WORKS: (RESEARCH PUBLICATIONS )

1. Correlation of serum malondialdehyde level with components of metabolic syndrome.
2. A study on premarital screening for beta thalassemia trait in hilly areas around salem.
3. Effect of different anticoagulants onHbA1C values by HPLC method at GMKMCH
4. Comparision of biochemical data obtained from Master Health Checkup patients and known Diabetic individuals-
5. Pole of UrinaryNeutrophil gelatinase associated Lipocalin as an earlier marker in detecting Diabetic Nephropathy
6. Serun Cystatin C: Abetter marker of Preeclampsia-
7. Study of Vitamin D status in normal healthy individuals and its association with Parathyroid Hormone levels
8. Role of Uric acid in detection of early renal function decline in Type 1 Diabetes
9. Ischemia modified Albumin:A recent biomarker in the diagnosis of Acute Coronary Syndrome
10. Serum Albumin and Uric acid estimation in Ischemic heart disease patients
11. Serun Copper Zinc ratio and Ceruloplasmin in South Indian Women of Thyroid disorders
12. Studyof Uric acid and Iron levels in Parkinsonism
13. Comparision between Sr. total, ionized and calculated Calcium at different albumin concentrations
14. Study of Insulin levels in Subclinical hypothyroidism
15. Liver enzymes and thyroid hormones profile in Chronic kidney disease
16. Evaluation of Plasma D-Dimer in type 2 Diabetes patients
17. Serum calcium and Magesium in Hypothyroid patients
18. Serum Calcium and Phosphorus levels in Chronic liver disease
19. Role of Uromodulin as a predictor of decline in Renal function
20. Study of serum Osteopondin levels in Chronic liver disease
21. Assesment of plasma Lipopolysaccharide binding protein levels in Non Diabetic Obese subjects
22. Serum Uric acid ,CK and LDH in Thyroid disorders
23. microalbinuria and albumin creatinine ratio in Type 2 DM
24. Serum Osteoprotegrin-can it predict Chronic Kidney Disease among Hypertensives?
25. Assesment of Thyroid Autoantibodies in type1 DM
26. Assesment of Maternal serum Docosahexaenoic acid in pre-eclampsia and uncomplicated pregnancies
27. Serum galectin 3-Can it be an early predictor of reduced ejection fraction among chronic heart failure patients
28. Serum endoglin-Is it an early predictor of diabetic nephropathy
29. Serum endocan levels in non alcoholic fatty liver disease -Is it influenced by glycemic status of the patients
30. Study of circulating alpha klotho protein levels in CKD patients from a tertiary care hospital
31. Evaluation of presepsin as a biomarker in neonatal sepsis

DEPARTMENTAL ROUTINE TEACHING ACTIVITIES

Periodical seminars are conducted in our department for 1 yr MBBS students.

Medal examination conducted in our department for 1yr MBBS students in july 2016.

Seminars, journal club, case discussion and lecture classes are held periodically for postgraduate students in our department.

Post graduates won 3rd prize in quiz competition held at young ambicon 2016 conference held at Hyderabad.

Poster presentation was done by two of our post graduates in young ambicon 2016 held at Hyderabad and also every year paper and poster presentations were done by our PG students in AMBICON and other National conferences.

BIOCHEMISTRY DEPARTMENT - FACULTY MEMBER

BIOCHEMISTRY DEPARTMENT - FACULTY MEMBER

PICTURES OF DEPARTMENT LABORATORY

PICTURES OF DEPARTMENT LABORATORY

PICTURES OF DEPARTMENT LABORATORY

PICTURES OF CME,QUIZ,DEPARTMENTAL ACTIVITIES

PICTURES OF CME,QUIZ,DEPARTMENTAL ACTIVITIES

PICTURES OF CME,QUIZ,DEPARTMENTAL ACTIVITIES

PICTURES OF CME,QUIZ,DEPARTMENTAL ACTIVITIES

PICTURES OF CME,QUIZ,DEPARTMENTAL ACTIVITIES